College of Photonics, National Yang Ming Chiao Tung University

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Faculty Lineup

Yi-Chun Chen

Title:Assistant Professor

Office Location:
R524
Extension:
#57829
E-mail:
chen52@nycu.edu.tw
Website:
https://sites.google.com/site/yichunchen52/
Expertise:
Dr. Chen has had extensive research experiences in the field of biophotonics. She has developed novel microscopy and imaging processing methods, to study important biomedical subjects, including: cancer cell metastasis, single particle tracking , cell rheology, and molecular kinetics of NPQ pathways in photosynthesis. She is also skilled in nano fabrication and metrology techniques for surface plasmon nano devices. She is now focused on developing advanced fluorescence lifetime imaging microscopy, miniaturized optoelectronic devices, and quantitative imaging analysis methods, with the goals to measure fast and dynamic physiology signals.
Research:

Education

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Publications

LIU, H.-T., LIN, W.-L., FENG, Y.-L., LIN, Y., CHENY.-C. 2017. Multidie LED combined with homogenizing optics to improve frequency response and intensity for FLIM applications. Journal of Microscopy.

WU, S.-H., NUNEZ, D., HU, S.-Y., DOMINGO, M. P., CHEN, Y.-C., WEI, P.-K., PARDO, J., GALVEZ, E. M. & CHIOU, A. 2014. The Effect of Acidic pH on the Inhibitory Efficacy of Peptides Against the Interaction ICAM-1/LFA-1 Studied by Surface Plasmon Resonance (SPR), Biosensors and Bioelectronics. 56, 159-166.

CHEN, Y.-C., MATSUBARA, S., CALIANDRO, R., GOVINDJEE & CLEGG, R. M. 2013. FLIM (Fluorescence Lifetime Imaging Microscopy) of Avocado Leaves during Slow Fluorescence Transient (the P to S Decline and the S to M Rise). Photosynthesis Research for Food, Fuel and the Future (ed. Lu C.). Zhejiang University Press, Springer-Verlag GmbH. 518-522.

CHEN, Y.-C., SPRING, B. Q. & CLEGG, R. M. 2012. Fluorescence Lifetime Imaging Comes of Age : How to Do It and How to Interpret It. Spectroscopic Methods of Analysis: Methods and Protocols (ed. Bujalowski W. M.). Humana Press Inc., New York, NY.

CHEN, Y.-C. & CLEGG, R. M. 2011. Spectral Resolution in Conjunction with Polar Plots Improves the Accuracy and Reliability of FLIM Measurements and Estimates of FRET Efficiency, Journal of Microscopy. 244, 21–37.

MATSUBARA, S., CHEN, Y.-C., CALIANDRO, R., GOVINDJEE & CLEGG, R. M. 2011. Photosystem II Fluorescence Lifetime Imaging in Avocado Leaves: Contribution of the Lutein-Epoxide Cycle and the Violaxanthin Cycle to ΔpH-dependent Fluorescence Quenching, Journal of Photochemistry and Photobiology B: Biology. 104(1-2), 271-284.

CHEN, Y.-C. & CLEGG, R. M. 2009. Fluorescence lifetime-resolved imaging. Photosynthesis Research, 102, 143-155.

CHEN, Y.-C., SPRING, B. Q., BURANACHAI, C., MALACHOWSKI, G. & CLEGG, R. M. 2009. What is behind all those lifetimes anyway, and where do we go from here? Proceeding of SPIE. 7183, 718302.

CHEN, Y.-C., SPRING, B. Q., BURANACHAI, C., TONG, B., MALACHOWSKI, G. & CLEGG, R. M. 2009. General Concerns of FLIM Data Representation and Analysis. FLIM Microscopy in Biology and Medicine (ed. Periasamy, A. and Clegg R.M.). Chapman & Hall/CRC, Boca Raton, FL. 291-339.

Patents

USA Patents

C. K. Lee, L. B. Yu, J. W. Liaw, D. Z. Lin, J. T. Tyan, Y. T. Chiu, C. T. Chen, C. C. Wu, C. S. Yeh, Y. C. Chang, K. T. Huang, Y. C. Chen, and Y. F. Wang, “Optical head capable of providing a subwavelength beams,” US Patent No. 7,792,006 B2 (September 7, 2010).

C. K. Lee, L. B. Yu, J. W. Liaw, D. Z. Lin, J. T. Tyan, Y. T. Chiu, C. T. Chen, C. C. Wu, C. S. Yeh, Y. C. Chang, K. T. Huang, Y. C. Chen, and Y. F. Wang, “Optical head capable of providing a subwavelength beams,” US Patent No. 7,288,776 (October 30, 2007).

Herman Rao, C. H. Hsu, J. N. Huang, C. K. Lee, W. J. Wu, W. H. Hsiao, C. K. Chen, Y. F. Chen, and Y. C. Chen, “Alert system and method for geographic or natural disasters utilizing a telecommunications network,” US Patent No. 6,914,525 (July 5, 2005).



ROC (Taiwan) Patents

Y. C. Chen,"Method for Measuring Real-Time Kinetics of Chemical Reactions,"ROC Patent No. I545313 (August 1, 2016).

C. H. Hsu, Herman Rao, C. K. Lee, W. J. Wu, W. H. Hsiao, C. K. Chen, Y. F. Chen, Y. C. Chen, and J. N. Hung, “Alert System and Method for Geographic or Natural Disasters Utilizing a Telecommunications Network,” ROC Patent No. I284864 (August 1, 2007).

C. K. Lee, L. B. Yu, J. W. Liao, D. J. Lin, J. T. Yeh, Y. T. Chiu, C. T. Chen, C. C. Wu, C. S. Yeh, Y. C. Chang, K. T. Huang, Y. C. Chen, and Y. F. Wang, “Optical Head Capable of Providing a Subwavelength Beams,” ROC Patent No. I266305 (November 11, 2006).

C. K. Lee, C. S. Yeh, K. C. Wu, D. J. Lin, Y. C. Chen, Y. F. Wang, P. T. Chou, J. W. Lee, and D. L. Yang, “Optical Head and Optical Etching Apparatus with Optical Head,” ROC Patent No. I258759 (July 21, 2006).

Advisees

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  • 112

    Can recruit recommended master students:2

    Recruitment of graduate students:2

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  • 111

    Can recruit recommended master students:1

    Recruitment of graduate students:2

    Details:Click To See

  • 110

    Can recruit recommended master students:2

    Recruitment of graduate students:2

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  • 109

    Can recruit recommended master students:2

    Recruitment of graduate students:2

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  • 108

    Can recruit recommended master students:2

    Recruitment of graduate students:2

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  • 107

    Can recruit recommended master students:2

    Recruitment of graduate students:2

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  • 106

    Can recruit recommended master students:1

    Recruitment of graduate students:3

    Details:Click To See