College of Photonics, National Yang Ming Chiao Tung University

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Faculty Lineup

Chen, Shean-Jen

Title:Distinguished Professor

Office Location:
R520
Extension:
#57825
E-mail:
sheanjen@nycu.edu.tw
Website:
https://apl440.web.nycu.edu.tw/

https://scholar.nycu.edu.tw/zh/persons/shean-jen-chen
Expertise:
Electro-Optical Signal Processing, Optronic Systems Integration, & Biophotonics System.
Research:
1. Advanced Nonlinear Optical Microscopy: Fast optical sectioning images for real-time applications, Imaging thick tissues with adaptive optics, Breaking diffraction limit for super-resolution imaging, & Multiphoton-induced laser ablation.
2. Three-dimensional Photolithography: Specific 3D microstructures & High-throughput microfabrication.

Education

  • School Name

    Country

    Department

    Degree

    From and To

  • UCLA

    國別:USA

    系所:Mechanical Engineering

    學位:PhD

    起迄年月:1997.1

  • Columbia University

    國別:USA

    系所:Mechanical Engineering

    學位:MS

    起迄年月:1992.2

  • National Taiwan University

    國別:Taiwan

    系所:Agricultural Machinery Engineering

    學位:BS

    起迄年月:1987.6

Experience

  • Service Agency

    Title

    Department

    Positions

    From and To

  • NYCU

    職稱:Professor & Dean

    部門/系所:College of Photonics

    擔任職務:

    起迄年月:2018.8~2021.7

  • NCTU

    職稱:Professor & Associate Dean

    部門/系所:College of Photonics

    擔任職務:

    起迄年月:2016.8~2018.7

  • National Cheng Kung University

    職稱:Director-General

    部門/系所:Center for Micro/Nano Science and Technology

    擔任職務:

    起迄年月:2012.8~2016.7

  • National Cheng Kung University

    職稱:Distinguished Professor

    部門/系所:Department of Engineering Science & Department of Photonics

    擔任職務:

    起迄年月:2012.8~2016.7

  • NCKU

    職稱:Deputy Director-General

    部門/系所:Research and Services Headquarter

    擔任職務:

    起迄年月:2011.2~2012.7

  • NCKU

    職稱:Director

    部門/系所:Technology Transfer & Business Incubation Center

    擔任職務:

    起迄年月:2011.2~2012.7

  • NCKU

    職稱:Deputy Director-General

    部門/系所:Center for Micro/Nano Science and Technology

    擔任職務:

    起迄年月:2009.8~2011.1

  • Massachusetts Institute of Technology

    職稱:Visiting Professor

    部門/系所:Department of Biological Engineering

    擔任職務:

    起迄年月:2008.6~2008.9

  • NCKU

    職稱:Professor

    部門/系所:Department of Engineering Science & Department of Photonics

    擔任職務:

    起迄年月:2007.8~2012.7

  • NCKU

    職稱:Associate Professor

    部門/系所:Department of Engineering Science & Department of Photonics

    擔任職務:

    起迄年月:2004.8~2007.7

  • NCKU

    職稱:Assistant Professor

    部門/系所:Department of Engineering Science & Department of Photonics

    擔任職務:

    起迄年月:2003.8~2004.7

  • National Central University

    職稱:Assistant Professor

    部門/系所:Department of Mechanical Engineering & Institute of Photonics

    擔任職務:

    起迄年月:2000.8~2003.7

  • National Synchrotron Radiation Research Center

    職稱:Assistant Research Scientist

    部門/系所:

    擔任職務:

    起迄年月:1998.1~2000.7

Publications

Current 5-year SCI Papers:
2016
H.-Y. Chang, C.-Y. Lin, C.-Y. Chang, H. Teng, P. J. Campagnola, and S.-J. Chen*, “Graphene oxide dot-based microstructures via dispersion and support of bovine serum albumin,” Optical Materials Express, vol. 6, no. 10, pp. 3193-3201, October 2016. (Impact Factor: 2.923)
T.-F. Yeh, W. L. Huang, C. J. Chung, I.T. Chiang, L.C. Chen, H. Y. Chang, W. C. Su, C. Cheng, S.-J. Chen, H. Teng, “Elucidating quantum confinement in graphene oxide dots based on excitation-wavelength-independent photoluminescence,” Journal of Physical Chemistry Letters, vol. 7, no. 5, pp. 2087-2092, June 2016. (Impact Factor: 8.539)
C.-Y. Chang, Y. Y. Hu, C.-Y. Lin, C.-H. Lin, H.-Y. Chang, S.-F. Tsai, T.-W. Lin, and S.-J. Chen*, “Fast volumetric imaging with patterned illumination via digital micro-mirror device-based temporal focusing multiphoton microscopy,” Biomedical Optics Express, vol. 7, no. 5, pp. 1727-1736, April 2016. (Impact Factor: 3.497)
T.-F. Yeh, C.-Y. Teng, L.-C. Chen, S.-J. Chen, and H. Teng, “Graphene oxide-based nanomaterials for efficient photoenergy conversion,” Journal of Materials Chemistry A, vol. 4, no. 6, p.p. 2014-2048, February 2016. (Impact Factor: 7.443)

2015
W.-T. Chang, S.-J. Chen, C.-Y. Chang, Y.-H. Liu, C.-H. Chen, C.-H. Yang, L. C.-S. Chou, J.-C. Chang, L.-C. Cheng, W.-S. Kuo, and J.-Y. Wang, “Effect of size-dependent photodestructive efficacy by gold nanomaterials with multiphoton laser,” ACS Appl. Mater. Interfaces, vol. 7, no. 31, pp 17318-17329, July 2015. (Impact Factor: 6.723)
R.-Y. He, V. Ajeti, S.-J. Chen, M. Brewer, and P. Campagnola, “Ovarian cancer cell adhesion/migration dynamics on micro-structured laminin gradients fabricated by multiphoton excited photochemistry,” Bioengineering, vol. 2, no. 3, pp. 139-159, July 2015. (Impact Factor: )
C.-Y. Teng, T.-F. Yeh, K.-I Lin, S.-J. Chen, M. Yoshimura, and H. Teng, “Synthesis of graphene oxide dots for excitation-wavelength independent photoluminescence at high quantum yields,” Journal of Materials Chemistry C, vol. 3, no. 17, pp. 4553-4562, May 2015. (Impact Factor: 4.696)
T.-F. Yeh, S.-J. Chen, H. Teng, “Synergistic effect of oxygen and nitrogen functionalities for graphene-based quantum dots used in photocatalytic H2 production from water decomposition,” Nano Energy, vol. 12, no. , pp. 476-485, March 2015. (Impact Factor: 10.325)
C.-Y. Lin, K.-M. Hsu, H.-C. Huang, T.-F. Yeh, H.-Y. Chang, C.-H. Lien, H. Teng, and S.-J. Chen*, “Multiphoton fabrication of freeform polymer microstructures containing graphene oxide and reduced graphene oxide nanosheets,” Optical Materials Express, vol. 5, no. 2, pp. 218-226, February 2015. (Impact Factor: 2.923)
Y. D. Sie, N.-S. Chang, P. J. Campagnola, and S.-J. Chen*, “Fabrication of three-dimensional multi-protein microstructures for cell migration and adhesion enhancement,” Biomedical Optics Express, vol. 6, no. 2, pp. 480-490, February 2015. (Impact Factor: 3.497)
C.-Y. Lin, P.-K. Li, L.-C. Cheng, Y.-C. Li, C.-Y. Chang, A.-S. Chiang, C. Y. Dong, and S.-J. Chen*, “High-throughput multiphoton-induced three-dimensional ablation and imaging for biotissues,” Biomedical Optics Express, vol. 6, no. 2, pp. 491-499, February 2015. (Impact Factor: 3.497)
M.-H. Lee, W.-P. Su, W.-J. Wang, S.-R. Lin, C.-Y. Lu, Y.-A. Chen, J.-Y. Chang, S.-S. Huang, P.-Y. Chou, S.-R. Ye, S.-J. Chen, H. He, T.-H. Liu, Y.-T. Chou, L.-J. Hsu, F.-J. Lai, S.-J. Chen, H.-C. Lee, D. Kakhniashvili, S. R. Goodman, and N.-S. Chang, “Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo,” Oncotarget, vol. 6, no. 6, pp. 3731-3751, February 2015. (Impact Factor: 6.627)
T.-W. Lin, Y.-H. Shih, S.-J. Chen, C.-H. Lien, C.-Y. Chang, T.-Y. Huang, S.-H. Chen, C. J. Jen, and Y.-M. Kuo, “Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice,” Neurobiology of Learning and Memory, vol. 118, no. , pp. 189-197, February 2015. (Impact Factor: 4.035)
C.-Y. Chang, B.-T. Ke, S.-Y. Lin, S.-Y. Chen, Y.-C. Lee, W.-C. Yen, and S.-J. Chen*, “Integrable FPGA-based Shack-Hartmann wavefront sensor,” was submitted to Applied Optics 2014. (Impact Factor: 1.649)

2014
C.-H. Lien, C.-Y. Lin, S.-J. Chen, and F.-C. Chien, “Dynamic particle tracking via temporal focusing multiphoton microscopy with astigmatism imaging,” Optics Express, vol. 22, no. 22, pp. 27290-27299, October 2014. (Impact Factor: 3.525)
L.-C. Cheng, N. G. Horton, K. Wang, S.-J. Chen, and C. Xu, “Measurements of multiphoton excitation cross sections for multiphoton microscopy,” Biomedical Optics Express, vol. 5, no. 10, pp. 3427-3433, September 2014. (Impact Factor: 3.497)
Y.-C. Li, T.-F. Yeh, H.-C. Huang, H.-Y. Chang, C.-Y. Lin, L.-C. Cheng, C.-Y. Chang, H. Teng, and S.-J. Chen*, “Graphene oxide-based micropatterns via high-throughput multiphoton-induced reduction and ablation,” Optics Express, vol. 22, no. 16, pp. 19726-19734, August 2014. (Impact Factor: 3.525)
L.-C. Cheng, C.-H. Lien, Y. D. Sie, Y. Y. Hu, F.-C. Chien, C. Xu, C. Y. Dong, and S.-J. Chen*, “Nonlinear structured-illumination enhanced temporal focusing multiphoton microscopy with a digital micromirror device,” Biomedical Optics Express, vol. 5, no. 8, pp. 2526-2536, August 2014. (Impact Factor: 3.497)
J.-N. Yih, Y. Y. Hu, Y. D. Sie, L.-C. Cheng, C.-H. Lien, and S.-J. Chen*, “Temporal focusing-based multiphoton excitation microscopy via digital micromirror device,” Optics Letters, vol. 39, no. 11, pp. 3134-3137, June 2014. (Impact Factor: 3.179)
C.-Y. Chang, L.-C. Cheng, H.-W. Su, Y. Y. Hu, K.-C. Cho, W.-C. Yen, C. Xu, C. Y. Dong, and S.-J. Chen*, “Wavefront sensorless adaptive optics temporal focusing-based multiphoton microscopy,” Biomedical Optics Express, vol. 5, no. 6, pp. 1768-1777, June 2014. (Impact Factor: 3.497)
T.-F. Yeh, C.-Y. Teng, S.-J. Chen, and H. Teng, “Nitrogen-doped graphene oxide quantum dots as photocatalysts for overall water-splitting under visible light illumination,” Advanced Materials, vol. 26, no. 20, pp. 3297-3303, May 2014. (Impact Factor: 15.409)
S.-F. Tsai, T.-Y. Huang, C.-Y. Chang, Y.-C. Hsu, S.-J. Chen, L. Yu, Y.-M. Kuo, C. J. Jen, “Social instability stress differentially affects amygdalar neuron adaptations and memory performance in adolescent and adult rats,” Frontiers in Behavioral Neuroscience, vol. 8, no. 27, pp. 1-8, 2014. (Impact Factor: 4.160)
K. Tilbury, C.-H. Lien, S.-J. Chen, and P. J. Campagnola, “Differentiation of Col I and Col III isoforms in stromal models of ovarian cancer by analysis of second harmonic generation polarization and emission directionality,” Biophysical Journal, vol. 106, no. 2, pp. 354-365, January 2014. (Impact Factor: 3.832)

2013
V. Ajeti, C.-H. Lien, S.-J. Chen, P.-J. Su, J. M. Squirrell, K. H. Molinarolo, G. E. Lyons, K. W. Eliceiri, B. M. Ogle, and P. J. Campagnola, “Image-inspired 3D multiphoton excited fabrication of extracellular matrix structures by modulated raster scanning,” Optics Express, vol. 21, no. 21, pp. 25346-25355, October 2013. (Impact Factor: 3.668)
C.-H. Lien, K. Tilbury, S.-J. Chen, and P. J. Campagnola, “Precise, motion-free polarization control in second harmonic generation microscopy using a liquid crystal modulator in the infinity space,” Biomedical Optics Express, vol. 4, no. 10, pp. 1991-2002, October 2013. (Impact Factor: 3.176)
C.-Y. Chang, B.-T. Ke, H.-W. Su, W.-C. Yen, and S.-J. Chen*, “Easily implementable FPGA-based adaptive optics system with state-space multichannel control,” Review of Scientific Instruments, vol. 84 no. 9, 095112, September 2013. (Impact Factor: 1.602)
Y.-C. Li, L.-C. Cheng, C.-Y. Chang, C.-Y. Lin, N.-S. Chang, P. J. Campagnola, C. Y. Dong, and S.-J. Chen*, “High-throughput fabrication of gray-level bio-microstructures via temporal focusing excitation and laser pulse control,” Journal of Biomedical Optics, vol. 18, no. 7, 075004, July 2013. (impact Factor: 2.881)
H.-Y. Tan, Y.-L. Chang, W. Lo, C.-M. Hsueh, W.-L. Chen, Ghazaryan, A. A. Ghazaryan, P.-S. Hu, T.-H. Young, S.-J. Chen, and C. Y. Dong, “Characterizing the morphologic changes in collagen crosslinked-treated corneas by Fourier transform-second harmonic generation imaging,” Journal of Cataract and Refractive Surgery, vol. 39, no. 5, pp. 779-788, May 2013. (Impact Factor: 2.527)
T.-F. Yeh, S.-J. Chen, C.-S. Yeh, and H. Teng, “Tuning the electronic structure of graphite oxide through ammonia treatment for photocatalytic generation of H2 and O2 from water splitting,” Journal of Physical Chemistry C, vol. 117, no. 13, pp. 6516-6524, April 2013. (Impact Factor: 4.814)
V. A. Hovhannisyan, P.-S. Hu, S.-J. Chen, C.-S. Kim, C.-Y. Dong, “Elucidation of the mechanisms of optical clearing in collagen tissue with multiphoton imaging,” Journal of Biomedical Optics, vol. 18, no. 4, 046004, April 2013. (Impact Factor: 2.881)
A. Ghazaryan, H. F. Tsai, G. Hayrapetyan, W.-L. Chen, Y.-F. Chen, M. Y. Jeong, C.-S. Kim, S.-J. Chen*, and C. Y. Dong*, “Analysis of collagen fiber domain organization by Fourier second harmonic generation microscopy,” Journal of Biomedical Optics, vol. 18, no. 3, 031105, March 2013. (Impact Factor: 2.881)
P.-S. Hu, A. Ghazaryan, V. Hovhannisyan, S.-J. Chen, Y.-F. Chen, C.-S. Kim, T.-H. Tsai, and C.-Y. Dong, “Imaging of biological tissues with pixel-level analysis of second-order susceptibility,” Journal of Biomedical Optics, vol. 18, no. 3, 031102, March 2013. (Impact Factor:2.881)

2012
V. A. Hovhannisyan, P,-S, Hu, H.-Y. Tan, S.-J. Chen*, and C.-Y. Dong*, “Spatial orientation mapping of fibers using polarization-sensitive second harmonic generation microscopy,” Journal of Biophotonics, vol. 5, no. 10, pp. 768-776, October 2012. (Impact Factor: 3.099)
W.-L. Chen, P,-S, Hu, A. Ghazaryan, S.-J. Chen*, T.-H. Tsai, and C.-Y. Dong*, “Quantitative analysis of multiphoton excitation autofluorescence and second harmonic generation imaging for medical diagnosis,” Computerized Medical Imaging and Graphics, vol. 36, no. 7, pp. 519-526, October 2012. (Impact Factor: 1.664)
T.-Y. Huang, L.-S. Lin, K.-C. Cho, S.-J. Chen, Y.-M. Kuo, L. Yu, F.-S. Wu, J.-I. Chuang, H.-I. Chen, and C. J. Jen, “Chronic treadmill exercise in rats delicately alters the Purkinje cell structure to improve motor performance and toxin-resistance in the cerebellum,” Journal of Applied Physiology, vol. 113, no. 15, pp. 889-895, September 2012. (Impact Factor: 3.484)
X. Chen, Y.-D. Su, V. Ajeti, S.-J. Chen, and P. J. Campagnola, “Cell adhesion on micro-structured fibronectin gradients fabricated by multiphoton excited photochemistry,” Cellular and Molecular Bioengineering, vol. 5, no. 3, pp. 307-319, September 2012. (Impact Factor: 1.443)
Y.-C. Li, L.-C. Cheng, C.-Y. Chang, C.-H. Lien, P. J. Campagnola, and S.-J. Chen*, “Fast multiphoton microfabrication of freeform polymer microstructures by spatiotemporal focusing and patterned generation,” Optics Express, vol. 20, no. 17, pp. 19030-19038, August 2012. (Impact Factor: 3.546)
P.-S. Hu, C.-M. Hsueh, P.-J. Su, W.-L. Chen, V. Hovhannisyan, S.-J. Chen*, T.-H. Tsai, and C.-Y. Dong*, “The use of second order susceptibility as contrast mechanism for label-free imaging of biological tissue,” IEEE Journal of Selected Topics in Quantum Electronics, vol. 18, no. 4, pp. 1326-1134, July/August 2012. (Impact Factor: 4.078)
W. Lo, W.-L. Chen, C.-M. Hsueh, A. A. Ghazaryan, S.-J. Chen, D. H.-K. Ma, C.-Y., H.-Y. Tan, “Fast Fourier transform based analysis of second harmonic generation image in keratoconic cornea,” Investigate Ophthalmology & Visual Science, vol. 53, no. 7, pp. 3501-3507, June 2012. (Impact Factor: 3.441)
C.-Y. Lin, C.-H. Lien, K.-C. Cho, C.-Y. Chang, N.-S. Chang, P. J. Campagnola, C. Y. Dong, and S.-J. Chen*, “Investigation of two-photon excited fluorescence increment via crosslinked bovine serum albumin,” Optics Express, vol. 20, no. 13, pp. 13669-13676, June 2012. (Impact Factor: 3.546)
W. Lo, A. Ghazaryan, C.-H. Tso, P.-S. Hu, W.-L. Chen, T.-R. Kuo, S.-J. Lin, S.-J. Chen, C.-C. Chen, and C.-Y. Dong, “Oleic acid-enhanced transdermal delivery pathways of fluorescent nanoparticles,” Applied Physics Letters, vol. 100, no. 21, 213701, May 2012. (Impact Factor: 3.794)
L.-C. Cheng, C.-Y. Chang, C.-Y. Lin, K.-C. Cho, W.-C. Yen, N.-S. Chang, C. Xu, C. Y. Dong, and S.-J. Chen*, “Spatiotemporal focusing-based widefield multiphoton microscopy for fast optical sectioning,” Optics Express, vol. 20, no. 8, pp. 8939-8948, April 2012. (Impact Factor: 3.546)
W.-S. Kuo, Y.-T. Chang, K.-C. Cho, K.-C. Chiu, C.-H. Lien, C.-S. Yeh, and S.-J. Chen*, “Gold nanomaterials conjugated with indocyanine green for dual-modality photodynamic and photothermal therapy,” Biomaterials, vol. 33, no. 11, pp. 3270-3278, April 2012. (Impact Factor: 7.604)
A. A. Ghazaryan, P.-S. Hu, S.-J. Chen, H.-Y. Tan, C.-Y. Dong, “Spatial and temporal analysis of skin glycation by the use of multiphoton microscopy and spectroscopy,” Journal of Dermatological Science, vol. 65, no. 3, pp. 189-195, March 2012. (Impact Factor: 3.520)
T.-W. Lin, S.-J. Chen, T.-Y. Huang, C.-Y. Chang, J.-I. Chuang, F.-S. Wu, Y.-M. Kuo, C. J. Jen, “Different types of exercise induce differential effects on neuronal adaptations and memory performance,” Neurobiology of Learning and Memory, vol. 97, no. 1, pp. 140-147, January 2012. (Impact Factor: 4.035)

Patents

Current 5-year SCI Patents:
1.陳顯禎、易政男、謝永達、胡瑜凌、鄭力中、李益誠、張家源,“利用數位微型反射鏡元件之多光子螢光激發顯微裝置”,中華民國 發明專利申請號:103120148 (申請日期:2014/06/11)。
2.陳顯禎、林俊佑、張芯語、葉德夫、鄧熙聖,“三維氧化石墨烯微結構與其製作方法”,中華民國 發明專利申請號:103128193 (申請日期:2014/08/15)。
3.陳顯禎、江安世、林俊佑、李培誥,"高通量雷射加工系統",中華民國,(申請日期:2015/08/4)
4.Shean-Jen Chen, Chun-Yu Lin, Hsin-Yu Chang, Te-Fu Yeh, His-Sheng Teng, " Fabrication of 3D Microstructures with Graphene Oxide "(Date of Application: Aug 26, 2014)

Advisees

  • Year

    Recommendation Quota

    Entrance Exam Quota

    Details

  • 113

    Can recruit recommended master students:2

    Recruitment of graduate students:2

    Details:Click To See

  • 112

    Can recruit recommended master students:1

    Recruitment of graduate students:4

    Details:Click To See

  • 111

    Can recruit recommended master students:0

    Recruitment of graduate students:3

    Details:Click To See

  • 110

    Can recruit recommended master students:2

    Recruitment of graduate students:2

    Details:Click To See

  • 109

    Can recruit recommended master students:2

    Recruitment of graduate students:2

    Details:Click To See

  • 108

    Can recruit recommended master students:2

    Recruitment of graduate students:2

    Details:Click To See

  • 107

    Can recruit recommended master students:1

    Recruitment of graduate students:3

    Details:Click To See

  • 106

    Can recruit recommended master students:2

    Recruitment of graduate students:3

    Details:Click To See